Is Clostridium difficile-associated infection a potentially zoonotic and foodborne disease?

Clostridium difficile associated disease

Direct gas-liquid chromatography of faecal specimens with isocaproic acid as a marker was used for the rapid diagnosis of Clostridium difficile associated diarrhoeal diseases. Ninety stools were examined and results were compared with conventional culture on selective medium and cytotoxin assay in tissue culture. Using a combined analysis of isocaproic acid and butyric acid peak heights we defi...

Clostridium difficile – A possible zoonotic link

Clostridium difficile Infection: A Worldwide Disease

Clostridium difficile, an anaerobic toxigenic bacterium, causes a severe infectious colitis that leads to significant morbidity and mortality worldwide. Both enhanced bacterial toxins and diminished host immune response contribute to symptomatic disease. C. difficile has been a well-established pathogen in North America and Europe for decades, but is just emerging in Asia. This article reviews ...

Clostridium Difficile infection and Antibiotic –Associated Colitis

Hospitalized patients receiving β lactam antibiotics develop diarrhea and higher rates reported in those receiving clindamycin. Clostridiumdifficile is recognized as a cause of antibiotic associated diarrhea, colitis and pseudomembranous colitis. Contributory factors include: advance age, severity of underlying illness.C.difficile has the ability to temporarily colonize newborn humans and calve...

Clostridium difficile infection and liver disease.

The rates of the predominantly hospital acquired infection, Clostridium difficile, have increased throughout the world. Several risk factors and susceptible patient populations have been identified. Patients with pre-existing liver disease represent an important cohort; recent evidence suggests that Clostridium difficile infection (CDI) is associated with a worse outcome and increased health ca...